This workshop explores the complex relationship between mental health and substance use among youth. Participants will examine common risk and protective factors that contribute to substance use and gain a deeper understanding of how mental health challenges, trauma, adverse childhood experiences, and environmental influences impact student behavior and decision-making. Through a trauma-informed lens, educators will learn evidence-based strategies and interventions to support students struggling with substance use, including approaches for individual counseling, small-group work, and school-wide prevention efforts. Participants will leave with practical tools to identify warning signs, build protective factors, and connect students to appropriate supports and resources.